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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1
All Species:
20.91
Human Site:
S452
Identified Species:
41.82
UniProt:
P11362
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11362
NP_056934.2
822
91868
S452
R
P
S
R
L
S
S
S
G
T
P
M
L
A
G
Chimpanzee
Pan troglodytes
XP_001171131
821
91764
T453
S
R
L
S
S
S
G
T
P
M
L
A
G
V
S
Rhesus Macaque
Macaca mulatta
XP_001090823
731
81824
S435
D
A
T
E
K
D
L
S
D
L
I
S
E
M
E
Dog
Lupus familis
XP_848780
820
91633
T452
S
R
L
S
S
S
G
T
P
M
L
A
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P16092
822
91962
S452
R
P
S
R
L
S
S
S
G
T
P
M
L
A
G
Rat
Rattus norvegicus
Q04589
822
91806
S452
R
P
S
R
L
S
S
S
G
T
P
M
L
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P21804
819
91558
S450
R
P
S
R
L
S
S
S
G
T
P
M
L
A
G
Frog
Xenopus laevis
P22182
812
90484
T448
R
R
L
S
S
S
G
T
P
M
L
S
G
L
S
Zebra Danio
Brachydanio rerio
Q90Z00
810
91023
S439
R
P
S
R
L
S
S
S
G
S
P
M
L
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
G686
T
V
S
T
T
G
T
G
G
T
D
P
A
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
Q596
E
P
S
P
Y
Q
I
Q
I
I
E
T
P
I
T
Sea Urchin
Strong. purpuratus
Q26614
972
110463
R613
P
L
F
G
G
R
N
R
L
T
S
S
L
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
85.5
98.9
N.A.
98.4
97.6
N.A.
N.A.
91.4
78.2
72.1
N.A.
30.6
N.A.
30.6
35.6
Protein Similarity:
100
99.7
86.7
99.3
N.A.
99.1
98.6
N.A.
N.A.
96.1
89.7
83.6
N.A.
45.4
N.A.
47.1
53
P-Site Identity:
100
6.6
6.6
6.6
N.A.
100
100
N.A.
N.A.
100
13.3
86.6
N.A.
26.6
N.A.
13.3
13.3
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
100
100
N.A.
N.A.
100
20
100
N.A.
33.3
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
17
9
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
9
0
9
0
0
0
0
% D
% Glu:
9
0
0
9
0
0
0
0
0
0
9
0
9
0
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
9
25
9
50
0
0
0
25
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
9
9
0
0
9
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
25
0
42
0
9
0
9
9
25
0
50
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
25
0
42
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
50
0
9
0
0
0
0
25
0
42
9
9
0
0
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
0
% Q
% Arg:
50
25
0
42
0
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
17
0
59
25
25
67
42
50
0
9
9
25
0
9
25
% S
% Thr:
9
0
9
9
9
0
9
25
0
50
0
9
0
9
9
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _